Is ACETEM a Safe and Approved Food Additive

Date:2025-06-30

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In the field of food innovation, ingredients that enhance product quality and shelf life are crucial. One such versatile ingredient is acetylated mono- and diglycerides (commonly known as ACETEM or European Food Additive Code E472a). But as consumer curiosity about food ingredients grows, a key question arises: Is ACETEM a safe and approved food additive? This blog will delve into the science and regulatory landscape to provide a comprehensive answer.

What Is ACETEM?

ACETEM (CAS NO. 97593-30-1) is an emulsifier derived from natural fats and oils, where acetic acid is added to mono- and diglycerides. This modification enhances its functional properties, making it highly effective at blending oil and water, stabilizing emulsions, and improving the texture and mouthfeel of various food products. Its applications range from baked goods and confectionery to whipped toppings and processed meats.

ACETEM E472a

The Safety Profile of ACETEM

The safety of any food additive is paramount and is rigorously evaluated by regulatory bodies worldwide. ACETEM emulsifier has undergone extensive scrutiny, and scientific consensus points to its safety for consumption.

Low Toxicity: Studies have shown that ACETEM exhibits very low acute oral toxicity. When consumed, ACETEM additive is extensively hydrolyzed in the gastrointestinal tract into its individual components—glycerol, fatty acids, and acetic acid—all of which are common dietary constituents and are metabolized by the body.

No Genotoxicity or Carcinogenicity Concerns: Comprehensive toxicological evaluations, including long-term studies, have indicated no evidence of genotoxic (damaging to DNA) or carcinogenic (cancer-causing) effects associated with ACETEM.

Acceptable Daily Intake (ADI): The European Food Safety Authority (EFSA) has concluded that there is no need for a numerical Acceptable Daily Intake (ADI) for E472a (ACETEM), E472b, and E472c, further affirming its low toxicological concern at typical usage levels. This means that based on available data, the consumption of ACETEM as a food additive does not pose a health risk.

Acetem emulsifier in food

Global Regulatory Approvals

E472a ACETEM's widespread use is backed by approvals from leading food safety authorities across the globe:

United States (FDA): In the U.S., Acetylated Mono- and Diglycerides are recognized as "Generally Recognized As Safe" (GRAS) by the Food and Drug Administration (FDA) under 21 CFR 172.828. This designation allows its use as a direct food additive without specific limitations, provided it adheres to good manufacturing practices. You can find more details on the FDA's Inventory of Food Contact Substances.

European Union (EU): In the EU, ACETEM ingredient is authorized as a food additive with the E-number E472a. Its use is permitted in various food categories under Annex II and Annex III of Regulation (EC) No 1333/2008 on food additives, with specific purity criteria defined in Commission Regulation (EU) No 231/2012. The EFSA has re-evaluated E472a and related esters, confirming their safety. Refer to the EFSA Journal for the re-evaluation of E 472a-f.

Codex Alimentarius: The Codex Alimentarius Commission, a joint initiative of the Food and Agriculture Organization (FAO) and the World Health Organization (WHO), includes ACETEM (INS No. 472a) in its General Standard for Food Additives (STAN 192-1995), providing a harmonized international standard for its use.

China: China's National Health Commission (NHC) has also approved ACETEM as a new food additive, demonstrating its growing acceptance and regulatory clearance in major global markets.

Conclusion: A Safe and Valued Food Additive

Based on comprehensive scientific evaluations and widespread regulatory approvals from prominent food safety authorities globally, Acetylated Mono- and Diglycerides (ACETEM or E472a) are considered safe and approved food additives. It plays an important role in enhancing the quality, texture, and shelf life of food products, thereby providing consumers worldwide with a diverse and consistent range of food products. As with all food additives, responsible use in accordance with regulatory guidelines ensures its continued safety and efficacy in the food supply.

At Chemsino, we offer ACETEM E472a with no minimum order quantity and the best price. Contact us now to get free samples.

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